Dante's Inferno: An Animated Epic

Nessus in the direct-to-DVD animated film Dante's Inferno: An Animated Epic was a centaur who resided around the Phlegethon, the boiling river of blood that comprised the first part of the Seventh Circle of Hell. She was a friend of Virgil who allowed he and Dante to ride across the treacherous river on her back. She is loosely based on a centaur by the same name from Greek mythology and Dante Alighieri's orignal Divine Comedy.